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SIGi001-A-7 Gene-edited iPSC line

Donor information

Gender:Female
Ethnicity:Caucasian

Disease status

Donor

Disease: normal

Disease/phenotype related genetic modifications

Disease: Frontotemporal dementia
Type of modification: Isogenic
Gene: MAPT
Chromosome location: 17q21.31
Nucleotide sequence HGSV: NM_005910.5:c.901C>T
Protein sequence HGSV: NP_005901.2:p.Pro301Ser
Zygosity: Heterozygous
Target locus modification: Mutated

General information

Depositor:Sigma-Aldrich
Cell line name:SIGi001-A-7
Cell line alternative names:iPSC0028 MAPT P301S 2G2B7
Biosamples ID:SAMEA4448730
hPSCreg name:SIGi001-A-7

Related lines

Derived from: SIGi001-A
All subclones of SIGi001-A: SIGi001-A-1, SIGi001-A-10, SIGi001-A-11, SIGi001-A-12, SIGi001-A-13, SIGi001-A-2, SIGi001-A-3, SIGi001-A-4, SIGi001-A-5, SIGi001-A-6, SIGi001-A-7, SIGi001-A-8, SIGi001-A-9
The parental iPSC line SIGi001-A can be sourced via Sigma as 'iPSC0028'.
At European Collection of Authenticated Cell Cultures (ECACC)
In stock
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