Log in

BIONi010-C-9 Gene-edited iPSC line

Donor information

Donor karyotype:46, XY

Disease status


Disease: normal

Disease/phenotype related genetic modifications

Disease: Alzheimer's disease
Type of modification: Gene knock-out
Gene: CD33
Chromosome location: 19q13.41
Delivery method: CRISPR-associated (CRISPR/Cas) System
Description: The CD33 gene has been knocked out. One base in exon one as well as 578 bases downstream (including whole exon 2) have been deleted. The basepair deletion leads to a frame shift. The larger deletion might not be necessary for a functional KO.

General information

Cell line name:BIONi010-C-9
Cell line alternative names:BIONi010-C CD33 KO
Biosamples ID:SAMEA4454012
hPSCreg name:BIONi010-C-9
Derivation country:Denmark

Related lines

Derived from: BIONi010-C
All subclones of BIONi010-C: BIONi010-C-10, BIONi010-C-11, BIONi010-C-12, BIONi010-C-13, BIONi010-C-15, BIONi010-C-17, BIONi010-C-18, BIONi010-C-19, BIONi010-C-2, BIONi010-C-24, BIONi010-C-25, BIONi010-C-3, BIONi010-C-4, BIONi010-C-5, BIONi010-C-6, BIONi010-C-7, BIONi010-C-8, BIONi010-C-9
From the same donor: BIONi010-A, BIONi010-B
KO for CD33. No larger chromosomal aberrations to be reported. Chr22: 1,4Mbp duplication in q11.23
At European Collection of Authenticated Cell Cultures (ECACC)
In stock
Cell Line Information Pack
A Cell Line Information Pack (CLIP) is created to communicate cell line specific information relating to restrictions on use to a user accessing cell lines from EBiSC. A CLIP contains information about a cell line including any specific third party obligations (TPOs) relating to, for example, intellectual property (IP) or the donor consent which affect the use of the cell line.