Log in

BIONi010-C-8 Gene-edited iPSC line

Donor information

Gender:Male
Donor karyotype:46, XY

Disease status

Donor

Disease: normal

Disease/phenotype related genetic modifications

Disease: Alzheimer's disease
Type of modification: Isogenic
Gene: TREM2
Chromosome location: 6p21.1
Nucleotide sequence HGSV: NM_018965.3:c.197C>T
Protein sequence HGSV: NP_061838.1:p.Thr66Met
Zygosity: Homozygous
Target locus modification: Mutated
Description: A homozygous T66M (rs201258663) mutation was interted into the TREM2 locus of BIONi010-C

General information

Depositor:Bioneer
Cell line name:BIONi010-C-8
Cell line alternative names:BIONi010-C Trem2 T66M, #Y5-80
Biosamples ID:SAMEA4454011
hPSCreg name:BIONi010-C-8

Related lines

Derived from: BIONi010-C
All subclones of BIONi010-C: BIONi010-C-10, BIONi010-C-11, BIONi010-C-12, BIONi010-C-13, BIONi010-C-15, BIONi010-C-17, BIONi010-C-18, BIONi010-C-19, BIONi010-C-2, BIONi010-C-24, BIONi010-C-25, BIONi010-C-3, BIONi010-C-4, BIONi010-C-5, BIONi010-C-6, BIONi010-C-7, BIONi010-C-8, BIONi010-C-9
From the same donor: BIONi010-A, BIONi010-B
No larger chromosomal aberrations to be reported. Chr22: 1,4Mbp duplication in q11.23
At European Collection of Authenticated Cell Cultures (ECACC)
In stock
Cell Line Information Pack
A Cell Line Information Pack (CLIP) is created to communicate cell line specific information relating to restrictions on use to a user accessing cell lines from EBiSC. A CLIP contains information about a cell line including any specific third party obligations (TPOs) relating to, for example, intellectual property (IP) or the donor consent which affect the use of the cell line.