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Cell Processing Information

Customers purchasing cell lines from EBiSC will benefit from:

EBiSC ensures the quality of all cell line banks using the following processes:

Standardised Cell Culture Conditions:

Core Quality Control Regime:

All QC tests have under gone qualification and are performed and documented to industry standards agreed by EFPIA. Core QC includes:

Batch specific Quality Control data is provided on a Certificate of Analysis supplied at cell line receipt, additional data sets are available at cells.ebisc.org.

All testing methods used by EBiSC have a finite sensitivity and lifespan. Therefore, recovered cultures should be treated as if potentially infectious and screened for pluripotency, cell line identity and chromosomal stability on a regular basis. Advice on appropriate methodologies can be obtained from EBiSC. EBiSC considers all iPSC lines as genetically modified as even non integrating systems may retain undetectable levels of reprogramming factors. All users should evaluate the cells with their local safety offices prior to use. It is possible that some lines may retain expression of reprogramming factors, and where this has been detected by EBiSC it will be made clear to you at the point of purchase. Guidance on methods for removal of reprogramming factors can be found in the EBiSC Cell Line User Protocol.